How It Works
Drinking HOTSHOT stimulates sensory neurons in the mouth, esophagus, and stomach.
Stimulated neurons send impulses to the spinal cord.
These impulses overpower and inhibit repetitive signals coming to and from the cramped muscle.
This stops repetitive signals and prevents and/or treats the cramp.
Our Scientific Team
Roderick MacKinnon, M.D.
Professor, Rockefeller and HHMI,
Nobel Prize 2003
Bruce Bean, Ph.D.
Harvard Medical School
Sports Advisory Board
Bob Murray, Ph.D. FACSM
Sports Science Insights
Chad Prusmack, M.D.
Chief of Neurosurgery,
Rocky Mountain Spine Clinic,
Scientific Advisory Board
HOTSHOT’s inventors, Dr. Rod MacKinnon and Dr. Bruce Bean, lead a renowned Scientific Advisory Board that guides HOTSHOT and its parent company Flex-Pharma, a Boston-based biotechnology company co-founded by
Alfred Sandrock, M.D.
Group Senior Vice President of Development Sciences and Chief Medical Officer, Biogen
Roger D. Tung, Ph.D.
President and Chief Executive Officer, Concert Pharmaceuticals
Christopher T. Walsh, Ph.D.
Professor Emeritus, Dept. of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
John Winkelman, M.D., Ph.D.
Associate Professor of Psychiatry, Harvard Medical School