Our Story

How Curiosity
Killed the Cramp

Watch the origin story of HOTSHOT featuring Nobel Prize-winning founder Dr. Rod MacKinnon.

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HOTSHOT 6 pack


HOTSHOT 12 pack


Meet Our Inventor

For Dr. Rod MacKinnon, a Nobel Prize-winning neuroscientist/endurance athlete, the invention of HOTSHOT was personal.

After surviving life threatening muscle cramps while deep sea kayaking off the coast of Cape Cod, he discovered that existing cramp remedies – that target the muscle – didn’t work. Calling upon his Nobel Prize-winning expertise on ion channels, Rod reasoned that preventing and treating cramps began with focusing on the nerve, not the muscle.

Five years of scientific research later, Rod has perfected HOTSHOT, the kick-ass, proprietary formulation of organic ingredients, powerful enough to stop muscle cramps where they start. At the nerve.

Today, Rod’s genius solution has created a new category in sports nutrition: Neuro Muscular Performance (NMP). It’s how an athlete’s nerves and muscles work together in an optimal way. HOTSHOT boosts your NMP to stop muscle cramps. So you can push harder, train longer and finish stronger.